Compute Nodes on GCP

Three kinds of nodes are supported on GCP. This page explains their features/cost/performance.

Compute Node

Description

4 P100

This is the most cost-effective node while sacrificing the performance marginally. User can run all Parabricks accelerated software except for DeepVariant.

4 V100

This node is very cost-effective and has high performance. User can run all Parabricks accelerated software on this node

8 V100

This is the fastest node on GCP for Parabricks software and can run all Parabricks accelerated software

Computing time and cost to run a 40x coverage NA12878 on a 4 P100 node

Tool

Time

Cost

bwa-sort-markdups-bqsr

100 minutes

$3.9

haplotypecaller

18 minutes

$0.67

Computing time and cost to run a 40x coverage NA12878 on a 4 V100 node

Tool

Time

Cost

bwa-sort-markdups-bqsr

88 minutes

$5.2

haplotypecaller

15 minutes

$0.9

DeepVariant

39 minutes

$2.3

Computing time and cost to run a 40x coverage NA12878 on a 8 V100 node

Tool

Time

Cost

bwa-sort-markdups-bqsr

60 minutes

$6.6

haplotypecaller

12.3 minutes

$1.3

DeepVariant

27 minutes

$2.95